position: EnglishChannel > Sci-Tech News > Article

Can plant-based vaccines help in the fight against COVID-19?

Source: International Communication Center for Science & Technology| 2020-05-18 19:28:49| Author: Zhao Hanbin Lu Zijian & China.org.

太阳城申博88登入,从2004年开始文学创作至今12年,他完成了16部长篇小说,七部改编成了漫画,四部作品正在改编为影视剧。  50年前,有大人物看了六龄童演的《三打白骨精》,评价甚高,于是乎拍成电影,演遍全国。本以为还了钱就没事了,哪想到,过了几天,陈冰再次收到催款短信,这次换了一个人。时间仅供参考,依自家烤箱为准

现阶段小米想以黑科技立身,消费者难以认同其突然爆发的十余项“黑科技”,消费者认知中三星、华为显然走在其前面。  中央第六巡视组专项巡视中国地震局党组工作动员会召开  根据中央统一部署,2016年6月30日下午,中央第六巡视组专项巡视中国地震局党组工作动员会召开。现在,我们的任务是发挥学科结构的优势,培养与社会创新相适应的人才。当日的启动仪式后,百名志愿者分别前往我市的13位抗战老兵家中,为他们送去米、面、油等生活物资、爱心礼品以及荣誉证书。

显然,火箭炮不可能单打独斗,而是集群射击。经过魏晋南北朝的演变,盛唐石狮彻底取代了天禄、辟邪等在帝王陵石雕中的主导地位,以万兽之王的形象呈现在世人面前,其蹲式造型更加中国化,对后世石狮雕刻产生了深远的影响。  然而,每次飞机降落到北京首都机场,于薇想到的总是,“终于回来了。艾米蔻负责休斯敦航天中心社交媒体和网站的管理工作,在和凯利隔空相守的日子,她成功促成空间站和社交媒体的互动,凯利不时将在太空拍摄的照片传到推特等社交网站。

A staff member tests samples of the COVID-19 inactivated vaccine at a vaccine production plant of China National Pharmaceutical Group (Sinopharm) in Beijing, capital of China, April 11, 2020. [Photo/Xinhua]

As potential COVID-19 vaccines enter human clinical trials, people have started to consider another problem: Once a vaccine is available, how can it be produced in sufficient quantities to meet the needs of billions of people around the world? 

Plant-based vaccines use genetic engineering technologies to introduce the antigen genes of pathogenic microorganisms into the plant genome, allowing the antigen protein to grow steadily within the edible part of the plant. This then creates an edible vaccine that can be taken orally. 

Since the birth of the world's first genetically engineered plant in 1983, more than 100 pathogenic microorganism antigen genes have been integrated into the plant genome, and some genetic products have been confirmed as immunogenic via animal experiments. Reports show that several dozen vaccines have now been produced in plants using genetic engineering technology. These plant-derived vaccines can be produced to target such contagions as the hepatitis B virus, foot-and-mouth disease virus, rabies virus glycoprotein, tubercle bacillus and rotavirus. 

Studies have shown that genes encoding hepatitis B virus surface antigens can be successfully expressed in tobacco, tomato, potato, lupin and lettuce plants. In recent years, Chinese researchers have introduced surface antigen genes for the hepatitis B virus into cherries, apples, potatoes and tomatoes to create genetically modified plants and express active hepatitis B virus surface antigen proteins. At present, the highest expression of the surface antigen is in potatoes. 

Luo Wen and Liu Ruiqi with the School of Biotechnology at Xi'an University introduced the main steps in developing plant vaccines. These involve cloning the target gene and connecting it to a vector that can be expressed in plants to construct an efficient plant expression vector; introducing foreign genes into plants, allowing the plants to carry specific antigen-encoding genes, achieving genetic transformation of plant cells, and culturing tissue of recipient cells and plant regeneration via genetic engineering technologies; detecting the expression of antigen protein genes in plants; and isolating, purifying and conducting purity identification of the target products; as well as testing the antigenicity and immunogenicity of plant expression products. 

Guan Zhengjun at the Key Laboratory of Resource Biology and Biotechnology in Western China, a lab jointly-built by China's Ministry of Education and Northwest University, told Science and Technology Daily that an edible vaccine based on genetically modified plants is one of the most promising directions for producing a new vaccine. Compared with traditional vaccines, plant-based vaccines are not only cheap, but the antigenic proteins expressed in them do not require extraction, purification and refrigeration, which greatly reduces the cost of production and transportation, and they are also relatively safe and effective. 

Plant-based genetic engineering technologies have gradually matured and brought broad prospects for the development of oral vaccines. For example, tomatoes — which are delicious, inexpensive and nutritious — are one of the most commonly used receptor materials for genetic engineering technologies. The ability for them to be eaten raw also prevents possible damage to foreign proteins during the heating process. 

However, at the same time, the safety and reliability of vaccines are always foremost concerns. In recent years, people have seen that there are still some uncertainties surrounding plant-derived oral vaccines, such as low expression of foreign proteins, possible digestion and degradation when taken orally, and safety issues. As such, anticipation for the technology has somewhat declined. How to solve these problems has become a major test for the development of future plant-based oral vaccines. 

(You can also read this article at: 太阳城申博88登入/www_china_org_cn/china/2020-05/15/content_76049250.htm)


Top News

  • The 2020 World Health Assembly(WHA) was held in a?special?period?of?time?when the outbreak of?COVID-19 put?the world in a complex situation, and the pandemic is?still spreading worldwide. Therefore, “how the world?responds?to the most serious global public health emergency since the end of WWII”,?has become the?focus of?discussion in the?international community.?

Israel-China Innovation Cooperation Benefits All

China is a model for making its vision to lead global innovation.China leads the development of infrastructure for an advanced technological environment, and the number of its people’s use of technologies and applications increases every year. In many fields, China is also a role model for global innovation.

A Future to Expect: International S&T Community Expresses High Hope in Cooperation with Peers in China English

According to the latest news from Science and Technology Daily (April 14th), two COVID-19 inactivated vaccines were just approved for a phase I & II combined clinical trial by the National Medical Products Administration (NMPA) of China, making them the first batch in this category. The two vaccines were developed respectively by Wuhan Institute of Biological Products Co., Ltd of Sinopharm and Sinovac Research & Development Co., Ltd together with research institutes.

太阳城申博88登入ICGEB Accepted 20,000 Protective Face Masks Donation from Chinese Partners

The ICGEB in Trieste, Italy has received a consignment of protective masks from its Chinese partners in Beijing and Taizhou, for distribution?to the local health authorities.

Copyright ? Science and Technology Daily, All Rights Reserved

mailto: yuhy@太阳城申博88登入 www.yinhe618.com

www.msc11.com 太阳城官方直营网登入 www.860msc.com 申博最新网址 申博在线直营网 申博太阳城代理开户登入
网上百家乐登入 申博电子游戏手机能玩吗 www.sbc66.com 申博微信支付充值 申博官网娱乐城登入 申博在线开户登入
www.508sun.com www.285msc.com 新版申博直营网 菲律宾太阳娱乐管理登入 申博娱乐登入 申博138登入